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The network and its partners The core teams The scientific program Supported projects Scientific indicators

History of transplantation  Aim 1 – Study of the mechanisms of allograft tolerance Aim 2 – Understanding and dissecting the causes of late graft loss Aim 3 – Transplantation in diabetic patients Aim 4 – New frontiers in transplantation (composite tissue graft, xenotransplantation, new immunosuppressive molecules, etc.) Aim 5 – The first European Validated Data Bank for transplantation Aim 6 – To foster relationships with biotechnology and pharmaceutical companies Aim 7 – Teaching the sciences of transplantation

FEB 3, 2012 NEXT Steering Committee - VIDEOCONFERENCE March 22, 2012 7th Scientific meeting in Nantes. → Consultez l'actualité

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The core teams of the CENTAURE network

In Lyon :

• Transplantation and Medicine Department: Pr JL. Touraine, Pr E. Morelon, Pr P. Cochat
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• Department of Surgery Transplantation: Pr JM. Dubernard, Pr X. martin, Pr O. Boillot
  Visit the website
  
  
• UMR-MA 103 : Pr M. Laville
  Visit the website
  
  
• Inserm 503 : Pr JF. Nicolas
  Visit the website des Hospices Civils de lyon

 

In Nantes :

• The Institute for Transplantation and Research in Transplantation (ITERT): Pr JP. Soulillou, including
  Visit the website de l’ITERT
  
  
  • the clinical nephrology and immunology Department :
    Pr JP. Soulillou
    
  • Inserm 643 : Pr I. Anegon

 

In Paris :

• Department for Adult Nephrology and Transplantation: Pr C. Legendre
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• Clinical Immunology Department: Pr L. Chatenoud
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• The Inserm Unit U580: Pr L. Chatenoud
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• The Inserm laboratory 775 : Pr P. Beaume
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• Anatomopathology Department: Pr N. Brousse
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Centaure RTRS Indicators

KEY FIGURES OF THE RTRS CENTAURE

 

PRIZES – SCIENTIFIC AWARDS

• J.P. Soulillou
  • 'Deneboube/Bayonne' prize from the National League against Cancer - 1989
  • L. Binet Prize (Foundation for 'la Recherche Médicale) - 1998
  • Medicine/Biology prize from the ‘Comité de Rayonnement français’ awarded by the Academy of Sciences - 1998
  • Prize Eloi Collery, Academy of Medicine - 2002
  • American Transplant Society Prizes won in 2001 and in 2005
  • Member of the jury for the prize of the ' Rayonnement Français' (Academy of Sciences)
    since 2004
  • Member of the ‘Institut Universitaire de France’ since 2002
  • The Transplantation Society Award for Outstanding Achievement Transplantation Sciences (Basic) - 2008
• J.M Dubernard
  • Genzyme Prize - Transplantation Society
  • The Medaware Prize - Transplantation Society - 2008
• A. Sirigu
  • Member of the Academy of Sciences of New York
• M. Michallet
  • Gallien prize – 2002
• L. Chatenoud
  • Odette Lemonon prize from the French Academy of Sciences - 1990
  • Jean Hamburger prize - 1996
  • Grodsky prize awarded by the Juvenile Diabetes Research Foundation - 2005
  • Pasteur-Weizmann/Servier prize - 2005
  • Prize of Roche Transplantation Society - 2006
• P. Beaune
  • Member of the Royal Academy of Sciences of Belgium

Patents

• Inserm U 643, Nantes
  1. ‘Proteins polyligands joined to a stable protein core (N° US5672486) Jean-Paul Soulillou – 30 septembre 2007
  2. ‘Process for non human transgenic mammal organs preparation in order to be transplanted in humans and nucleotide sequences for establishing this process’ (Nb WO1997FR01340) Bernard Vanhove – July 29, 1998 (Nb JP2000516804T) –December 19, 2000
  3. ‘Analysis process of T lymphocites via lymphocites T receptors from an organism’ TcLandscape patent (Nb: WO 02/084567, INSERM) Jean-Paul Soulillou, Sophie Brouard, Marc-André Delsuc, Marina Guillet ; worldwide exclusive license – April 13, 2001
  4. sc28AT patent ‘anti-CD28 antibody’ (Nb: WO02/051871) Jean-Paul Soulillou, Geneviève Laflamme, Bernard Vanhove – worldwide exclusive license – December 26, 2001
  5. Patent ‘Chip dedicated to tolerance’ ‘Méthods and compositions for determining a graft tolerant phenotype in a subject’ (Nb: WO2005070086) Provisional Patent Application Serial Nb 60/571,471 May 14, 2004 Provisional Patent Application serial Nb 60/538,439 January 21, 2004 (INSERM/Stanford University) Sophie Brouard, JP Soulillou, E. Mansfield, M Sarwal. Licence co-exclusive (under process) – January 21, 2004
  6. ‘HLA-E production, soluble by endothelial cells and activated melanoma lines: a new marker and an immunoregulating molecule’ (Inserm patent Nb: EP042930230), B. Charreau ; December 17, 2004 (license approval)
  7. ‘Diagnosis of immune tolerance state in renal transplantation thanks to transcriptional analysis with dedicated chip’ TcTol patent Provisional Patent Application Serial Nb.05291215.1, Inserm, S. Brouard, JP Soulillou, D. Baeten, C. Braud, M. Giral, J. Léger. Worldwide and exclusive license (under processed) – June 7, 2005
  8. ‘TRIBB-1 and diagnosis of chronic rejection in human renal transplantations’ Inserm/TcLand – Provisional Patent Application Serial Nb. 60/808, 122, Inserm – S. Brouard, JP. Soulillou, J. Asthon-Chess. May 25, 2006
     
     
• Inserm U 775, Paris
  1. HNF1 alpha as a tumor suppressor gene and diagnostic and therapeutic applications thereof 05-11 2003 Patent Nb 02292054.0-2402P Laurent Puig
  2. P450 specific probes and primers and biological applications thereof 11-06 2003 Patent Nb 01969307.6-2405-EPO107056 Cytochromes I de Waziers
     
     
• Inserm U 503, Lyon
  1. Method for histological color images analysis for automatic quantification and characterization of interstitial fibrosis. Patent Nb 2004292513-1 ; E. Morelon 2004

NEW COMPANIES CREATED BY THE CENTAURE CORE CENTERS

• Lynatech : 1991 in Nantes
• IDBC : computer programs and software for medical data banks, 2001 in Nantes
• TcLand : Analysis of T-cells response, 2002 in Nantes
• Technomed international : Lithotripsy and focused ultrasound technology, 1987 in Lyon

 

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