SPACES |
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Presentation
The network and its partners
History of transplantation  |
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Supported projects: Joint Program of Activity, 2nd Cycle
The list of projects included in the Joint Program of Activities (2nd cycle) of the foundation is described below. Projects – from November 2008 to October 2009 – have been accepted and approved by the different committees of the foundation and in particular by the International Scientific Advisory Board and by the last Steering Committe which took place in Paris on October 24, 2008. Project are listed under 5 main thematic fields.
DIVAT
- Organizing Lyon core center to provide data for the DIVAT kidney and pancreas data bank - Xavier Martin
- The DIVAT network project: a composite platform for kidney and pancreas transplantation research - Magali Giral
- The DIVAT program at Necker Hospital - Christophe Legendre
BIOmarkers
- Proteolytic superantibodies (sPAb) as non invasive test to predict the kinetic of CAN - Olivier Thaunat
- Characterization of the HLA antibodies developped against the donor after kidney transplantation - Maryvonne Hourmant
- Prospective randomized study of CNI weaning in selected long term kidney recipients. Validation of biomarkers of risk in transplantation - Jean-Paul Soulillou
- Validation of pronostic biomarkers of long term graft outcome at 1 year after transplantation - Sophie Brouard
- Quantification of interstitial fibrosis by image analysis on routine renal biopsy - Eric Thervet
Immunointervention / preservation
- Targeting intragraft lymphoid neogenesis to prevent chronic rejection - OlivierThaunat
- Evaluation of new protocols for kidney preservation using a perfusion machine - Lionel Badet
- Modulation of alloimmune response by mesenchymal stem cells: mechanisms responsible for MSC-induced immune suppression in vivo and interactions with immunosuppressive drugs - Emmanuel Morelon
- Immunosuppression and tolerance induction by selective blockade of CD28 - Bernard Vanhove
- Advantage of co-grafting MSC with neurons in intracerebral restaurative strategies - Philippe Naveilhan
- Induction of tolerance to allogeneic islet transplantation in autoimmune diabetic mice by treatment associating carbon monoxide (CO)-treated dendritic cells (DCs) and anti-CD3 Mab - Ignacio Anegon
- Immune mechanisms underlying the tolerogenic effect of CD3-specific antibodies - Lucienne Chatenoud
Mechanistic study on host to graft/ immune response / tolerance / graft loss
- In vivo monitoring of pancreatic beta cells and T lymphocytes during allografts and autoimmune reactions - Charles Thivolet
- Determine the role of CLEC-1, a C-type lectin receptor, in immune tolerance - Elise Chiffoleau
- Dendritic cells and allograft tolerance: from basic DC biology to preclinical application - Régis Josien
- Deciphering the role of peripheral B cells in operationally tolerant patients - Sophie Brouard
- Function and regulation of non classical MHC class I molecules expressed on endothelial cells: impact for kidney transplant outcome and monitoring - Béatrice Charreau
MISCELLANEOUS
- Study of the acute antibody mediated rejection in alloimmunized primates - Gilles Blancho
- Knee transplantation in piglet: development of an experimental model of allotransplantation and evaluation of the immunological response in an allogeneic situation - Aram Gazarian
- Isolated pancreas transplant vs intensive inlulin in type 1 nephropatic diabetics - Diego Cantarovich
- Structuration of CENTAURE centers: supports for flow cytomety core facility and network/computer management for Nantes CENTAURE teams - Jean-Paul Soulillou